Preservative-Free OTC Dry Eye Relief

Early Access Now Open for Licensed Eye Care Professionals

SilkTears™ is a formulated by eye care professionals, preservative-free eye drop formulated for the temporary relief of dryness and irritation. Limited early access eye drops available.

Limited early access for licensed ECPs only

SilkTears dry eye drops

Why SilkTears™?

SilkTears™ is a preservative-free eye drop developed with provider and patient needs in mind — formulated for temporary relief of dryness and irritation, and made in accordance with FDA OTC Monograph M018 for ophthalmic lubricants.

What is SilkTears™?

SilkTears™ is a sterile, preservative-free OTC eye drop formulated to relieve dryness, irritation,
and discomfort caused by environmental factors and everyday strain.

Single-use, sterile
packaging

Silk-derived
technology

Smooth
application

Formulated by
practicing clinicians

Made in the USA,
cGMP-compliant

Preservative-Free,
6-Ingredient Formula

Single-use, sterile
packaging

Silk-derived
technology

Smooth
application

Formulated by
practicing clinicians

Made in the USA,
cGMP-compliant

Preservative-Free,
6-Ingredient Formula

EXCLUSIVE EARLY ACCESS PROGRAM

SilkTears™ is currently available in limited quantities to licensed professionals only. Request access to evaluate in-practice use and experience the benefits firsthand.

This field is for validation purposes and should be left unchanged.

I feel truly confident recommending SilkTears to my patients for their dry eye symptoms. The feel, the formulation, the feedback—it checks all the boxes.

— Dr. Paul Karpecki, OD, Medical Director

Formulation Overview

SilkTears™ is an over-the-counter lubricating eye drop that meets FDA OTC monograph requirements for ocular lubricants and is intended for the temporary relief of dryness and irritation.

Its preservative-free formulation uses a silk-derived protein (Amlisimod) as an inactive wetting agent excipient and includes only permitted ingredients under the FDA’s OTC Monograph M018.

What’s Inside:
Our Carefully Selected Ingredients

SilkTears™ is formulated under the FDA’s OTC Monograph M018 for ophthalmic lubricants, using only permitted ingredients — with nothing unnecessary, nothing harsh.

Every component in SilkTears™ is selected with intention: to meet strict FDA requirements for over-the-counter eye drops, to align with modern patient expectations for clean, minimalist formulations, and to support safe, gentle use — even on the most sensitive eyes.

  • No synthetic preservatives.
  • No PEGs.
  • No parabens.
  • No surfactants.
  • No ingredients you can’t pronounce.

Just thoughtful formulation, guided by science and built for today’s dry eye patient.

Active Ingredient

Glycerin (0.2%) – A well-established ophthalmic lubricant derived from vegetable and fruit oils. Used to temporarily relieve dryness and irritation by protecting and moisturizing the ocular surface.

Inactive Ingredients

Purified Water – Acts as the base for the formulation — clean, sterile, and essential for isotonic balance.

Amlisimod (silk-derived protein) – A highly water-soluble protein hydrolysate produced from the natural silk cocoon. Included as an inactive wetting agent to support comfortable application. No therapeutic claims are made.

Dextrose – Helps maintain osmolality to support ocular comfort and formulation stability.

Magnesium Chloride – A mineral salt that helps balance pH and enhance formulation stability.

Sodium Acetate – A buffering agent that assists in maintaining a comfortable pH and stabilizes the formulation.

May also contain trace amounts of hydrochloric acid and/or sodium hydroxide to adjust pH during manufacturing.

Minimal Ingredients. Maximal Intent.

SilkTears™ was created by clinicians, for patients who read the label. Our focus isn’t marketing fluff — it’s formulation integrity. Each ingredient serves a purpose. And none are included to do anything beyond what’s permitted in a compliant OTC product.

SilkTears™ is preservative-free, single-use, and Manufactured in the USA in accordance with current Good Manufacturing Practices (cGMP).

FOR DRY EYE SUFFERERS

Relief Is Coming

If you experience dry, irritated eyes, ask your provider about SilkTears™.