Preservative-Free OTC Dry Eye Relief
Early Access Now Open for Licensed Eye Care Professionals
SilkTears™ is a doctor-formulated, preservative-free eye drop designed to soothe and protect eyes affected by dryness and irritation. Limited early access eye drops available.
Limited early access for licensed ECPs only
Why SilkTears™?
Born from years of clinical frustration with the limitations of existing OTC drops, SilkTears™ was developed by eye care professionals, for eye care professionals — with patients in mind from day one.
The result is a new model in OTC care: a preservative-free, science-forward eye drop that prioritizes provider trust, clinical performance, and patient comfort from day one.
What is SilkTears™?
SilkTears™ is a sterile, preservative-free OTC eye drop formulated to relieve dryness, irritation,
and discomfort caused by environmental factors and everyday strain.
Single-use, sterile
packaging
Silk-derived
technology
Smooth
application
Formulated by
practicing clinicians
Made in the USA,
cGMP-compliant
Preservative-Free,
6-Ingredient Formula
Single-use, sterile
packaging
Silk-derived
technology
Smooth
application
Formulated by
practicing clinicians
Made in the USA,
cGMP-compliant
Preservative-Free,
6-Ingredient Formula
EXCLUSIVE EARLY ACCESS PROGRAM
SilkTears™ is currently available in limited quantities to licensed professionals only. Request access to evaluate in-practice use and experience the benefits firsthand.
I feel truly confident recommending SilkTears to my patients for their dry eye symptoms. The feel, the formulation, the feedback—it checks all the boxes.
Formulation Overview
& Educational References
SilkTears™ is an over-the-counter lubricating eye drop that meets FDA OTC monograph requirements for ocular lubricants and is intended for the temporary relief of dryness and irritation. Its preservative-free formulation uses a silk-derived protein as an inactive wetting agent excipient.
About the external research below: these publications discuss silk-derived materials in general, including preclinical and clinical research settings. They do not evaluate SilkTears™, and their findings should not be interpreted as claims about SilkTears™’ performance or as treatment claims. SilkTears™’ only intended use is the temporary relief of dryness and irritation as permitted under the OTC monograph for ophthalmic lubricants.
Silk-Derived Protein-4 Versus Vehicle Control in Treating Patients With Moderate to Severe Dry Eye Disease: A Randomized Clinical Trial
American Journal of Ophthalmology, 2025 Read on PubMed
Effects of Silk Fibroin in Murine Dry Eye
Scientific Reports, 2017 Read on Nature
Comprehensive Physicochemical Characterization and in Vitro Human Cell Culture Studies of an Innovative Biocompatible and Biodegradable Silk-Derived Protein Hydrolysate, SDP-4
ACS, 2025 Read on Pubs
A Review of the Emerging Role of Silk for the Treatment of the Eye
International Journal of Molecular Sciences, 2018 Read on PMC
Effect of silk fibroin protein hydrolysis on biochemistry, gelation kinetics, and NF-kB bioactivity in vitro
ScienceDirect, 2024 Read on ScienceDirect
What’s Inside:
Our Carefully Selected Ingredients
SilkTears™ is formulated under the FDA’s OTC Monograph M018 for ophthalmic lubricants, using only permitted ingredients — with nothing unnecessary, nothing harsh.
Every component in SilkTears™ is selected with intention: to meet strict FDA requirements for over-the-counter eye drops, to align with modern patient expectations for clean, minimalist formulations, and to support safe, gentle use — even on the most sensitive eyes.
- No synthetic preservatives.
- No PEGs.
- No parabens.
- No surfactants.
- No ingredients you can’t pronounce.
Just thoughtful formulation, guided by science and built for today’s dry eye patient.
Active Ingredient
Glycerin (0.2%) – The only FDA-listed active ingredient in our formula. Glycerin is a widely used ophthalmic lubricant derived from vegetable and fruit oils. It forms a temporary, soothing layer over the eye surface to relieve dryness and irritation.
Inactive Ingredients
Purified Water – A sterile, high-purity base for the formulation. Water is essential to achieving isotonic balance and overall drop tolerability.
Silk-Derived Protein-4 (SDP-4) – A highly water-soluble silk protein hydrolysate, included as an excipient wetting agent. SDP-4 is produced from the natural silk cocoon and contributes to the smooth, hydrating feel of the drop. It does not serve an active role per the OTC monograph, but is included to support patient comfort.
Dextrose – A simple sugar that helps fine-tune osmolality for a more comfortable experience on instillation.
Magnesium Chloride – A mineral salt that helps balance pH and formulation stability.
Sodium Acetate – A buffering agent used to maintain consistent, eye-friendly pH over time.
May also contain trace amounts of hydrochloric acid and/or sodium hydroxide to adjust pH during manufacturing.
Minimal Ingredients. Maximal Intent.
SilkTears™ was created by clinicians, for patients who read the label. Our focus isn’t marketing fluff — it’s formulation integrity. Each ingredient serves a purpose. And none are included to do anything beyond what’s permitted in a compliant OTC product.
SilkTears™ is preservative-free, single-use, and manufactured in FDA-registered cGMP facilities in the USA
FOR DRY EYE SUFFERERS
Relief Is Coming
If you experience dry, irritated eyes, ask your provider about SilkTears™.
